From the railway station:
From the main exit of the train station - By mini-bus (called "marshrutka") No. 181 (also called 7+18) to "Poltavska" stop (around 20 min.). Then go by Pimonenka street to the American Embassy Consular Section at 6, Pimonenka str. Hostel "Kiev" is behind the Embassy in the 9-storey building. Reception is on the 8th floor.
From Boryspil International Airport:
Take the Shuttle ("Atass" company) bus to metro "Kharkivska" ("green" line), then by metro to "Lukyanivska" station (same "green" line), then by trolley-bus or marshrutka No. 16 or 18 back towards Independence square to "Poltavska" stop (1hour 20min.)
From Kiev Domestic Airport:
By minibus (called "marshrutka") to "Metro "Dorogozhichi" stop, then by marshrutka No. 406 to "Poltavska" stop (50 min.)
From the Central bus terminal:
Any kind of transport or walk to "Lybidska" metro station ("blue" line), then to "Maydan Nezalezhnosti" metro station ("blue" line), then by trolley-bus or minibus (called "marshrutka") No. 16 or 18 up to "Poltavska" stop (35 min.)